Paolo Zuliani Computer Science Department Carnegie Mellon University Title: Statistical Model Checking for Biological Systems Abstract: Computational modeling is increasingly used to gain insights into the behavior of complex biological systems, such as signaling pathways. Moreover, powerful verification methods such as model checking have been recently applied to the analysis of biological system models. In this talk we exemplify this approach on several signaling pathways important in cancer. We first use the rule-based BioNetGen language to build computational models of the pathways. Then we apply statistical model checking for verifying temporal logic properties of the models. In particular, the use of statistical model checking enables us to verify large systems in a scalable way.