[FOM] constructivism and physics (reply to Gordeew)
joeshipman@aol.com
joeshipman at aol.com
Sun Feb 12 19:47:25 EST 2006
Lew, how do you know that the "solution" achieved in "natural reality"
is really optimal? Might it not just be optimal among the solutions
that can arise from a long string folding, while there are lower-energy
solutions which cannot be reached by a feasible "path" starting from a
straightened string?
-- JS
-----Original Message-----
From: Lew Gordeew <legor at gmx.de>
...
It might not necessarily be related to physics, but let me remind this
empirical phenomenon.
Protein folding problem:
Given a stable protein as a long string over 20 amino acids identify its
unique 3D spatial structure with minimal energy.
This (obviously constructive) open problem in biology is NP-hard under
most
mathematical models, and yet in "natural reality" it takes only a few
seconds to achieve the solution. Nobody knows how this is done in
nature, so
people are testing genetic algorithms to approximate the natural folding
procedure.
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